Curriculum Vitae

Last Updated: 11/09/2020.

Education

• 2019 M.S. Bioinformatics, University of Texas at El Paso (UTEP)
• 2016 B.S. Biochemistry, University of Texas at El Paso (UTEP)

Appointments

Scripps Research

• 07/2020 - Present Research Programmer, Su / Wu Labs

GlaxoSmithKline

• 08/2019 - 02/2020 Co-op, Medical Insights: Data Analysis and Visualization / DevOps Engineering
• 05/2019 - 08/2019 Intern, Protein Design and Informatics
• 05/2018 - 08/2018 Intern, Protein Design and Informatics

University of Texas at El Paso

• 01/2019 - 05/2019 Teaching Assistant, UTEP Bioinformatics Program
• 01/2018 - 05/2019 Graduate Research Assistant, Dr. Suman Sirimulla, UTEP School of Pharmacy
• 08/2016 - 08/2017 Graduate Research Assistant, Dr. Ming-Ying Leung, UTEP Bioinformatics Program
• 03/2014 - 08/2015 Undergraduate Research Assistant, Dr. Ricardo Bernal, UTEP Department of Chemistry

Publications

Xian, Y., Avila, R., Pant, A., Yang, Z., & Xiao, C. (2020). The Role of Tape Measure Protein in Nucleocytoplasmic Large DNA Virus Capsid Assembly. Viral Immunology. doi:10.1089/vim.2020.0038

Presentations

Posters

• 2018 Evaluating the effectiveness of mixed probe molecular dynamics for cryptic pocket detection. GSK Intern/Co-op symposium, Upper Providence, Pennsylvania, USA.
• 2018 Automated workflow for reproducible analysis of protein-ligand scoring functions. OpenEye CUP XVIII, Santa Fe, New Mexico, USA.
• 2017 In silico evaluation of human OX2 orexin receptor (hOX2R) inhibitors using AutoDock and Glide. 12th Annual NMBIST Symposium on Microbiomics, Santa Fe, New Mexico, USA.
• 2016 Comparison of AutoDock and Glide in docking Suvorexant to the crystal structure of hu- man OX2 receptor (hOX2R) 19th UTEP/NMSU Workshop on Mathematics, Computer Science, and Computational Sciences, El Paso, Texas, USA.
• 2015 A point mutation in the Phi-EL chaperonin alters ring separation and protein folding activity. UTEP COURI Symposium, El Paso, Texas, USA.

Workshops

• May 7-9, 2018 MMTF Workshop & Hackathon, San Diego Supercomputer Center (SDSC), San Diego, CA
• August 28, 2019 Dashboard in a Day, Microsoft, Malvern, PA

Awards

• 2011 Presidential Scholarship, from The University of Texas at El Paso
• 2018 MMTF Workshop Travel Award, funded by the NIH Big Data to Knowledge (BD2K) initiative

Skills

Programming Languages

• Python
• UNIX shell (BASH)
• R
• MySQL
• Java

Other Technologies

• Git
• Docker
• High Performance Computing (HPC)
• Databricks
• Microsoft Azure
• Continuous Integration

Protein & Molecular Informatics

• Cheminformatic toolkits: RDKit, OpenEye
• Molecular docking: AutoDock Vina, Glide
• Molecular viewers: PyMol, Chimera, NGLView, VMD, Schrödinger Maestro
• Pocket detection: MOE Site Finder, Schrödinger SiteMap

Structural Biology

• Cryo-EM image processing: Relion 3, EMAN2
• Molecular Biology: Protein expression, Protein purification.